ACTIVE INGREDIENTS AND MOLECULAR TARGETS OF TARAXACUM MONGOLICUM AGAINST HEPATOCELLULAR CARCINOMA: NETWORK PHARMACOLOGY, MOLECULAR DOCKING, AND MOLECULAR DYNAMICS SIMULATION ANALYSIS

Active ingredients and molecular targets of Taraxacum mongolicum against hepatocellular carcinoma: network pharmacology, molecular docking, and molecular dynamics simulation analysis

Background Taraxacum mongolicum (TM) is a widely used herb.Studies have reported that TM exhibits growth-inhibitory and apoptosis-inducing on multiple tumors, including hepatocellular carcinoma (HCC).The active ingredients, targets, and molecular mechanisms of TM against HCC need to be further elucidated.Methods We identified the active Heat Patche

read more

SVD identifies transcript length distribution functions from DNA microarray data and reveals evolutionary forces globally affecting GBM metabolism.

To search for evolutionary forces that might act upon transcript length, we use the singular value decomposition (SVD) to identify the length distribution functions of sets and subsets of human and yeast transcripts from profiles of mRNA abundance levels across gel electrophoresis migration distances that were previously measured by DNA microarrays

read more